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China has reported disappointing economic data for the month of April, underscoring the extensive damage Covid lockdowns have wreaked on the country.To get more news about china coronavirus update, you can visit shine news official website.

The world's second largest economy reported shocking drops in retail sales and factory production, widely missing market expectations.
Retail sales plunged 11.1% in April from a year ago, according to China's National Bureau of Statistics on Monday. That was well below the 6.1% drop forecast in a Reuters survey of economists, and also much lower than the 3.5% decrease seen in March.This marks the worst contraction in industrial production since February 2020, when China's economy came to a near standstill during the initial coronavirus outbreak.
Unemployment also surged to the second highest level on record.The urban jobless rate hit 6.1% in April, up from 5.8% in March — which was already at a 21-month high. The only time China's jobless rate was higher was in February 2020.
Young people have been finding it especially hard to find jobs, the data showed, with the unemployment rate for those between 16 to 24 years of age rising to 18.2% — the highest ever.
Rising unemployment is a warning sign for the ruling Communist Party given the risk of social and political instability.
"After all, zero-Covid at the cost of surging unemployment is a hard sell politically," said Larry Hu, chief China economist for Macquarie Capital.
The government expects the economy to rebound this month.
"Economic performance" in May will improve, said NBS spokesperson Fu Linghui on Monday.
"As the outbreaks are under control and people's life return to normal, pent-up consumption will be gradually released," he said.China's economy was off to a solid start in 2022, recording 4.8% growth for the first quarter.
But Beijing's efforts to curb its worst Covid outbreak in two years have dealt a hefty blow to activity since March, and economists now expect GDP to shrink this quarter.
So far, at least 31 cities in the country remain under full or partial lockdown, according to CNN's latest calculations. Shanghai, the country's financial center and a manufacturing hub, has been under lockdown for more than six weeks. During this period, many companies have been forced to suspend operations, including automakers Tesla (TSLA)and Volkswagen (VLKAF) and iPhone assembler Pegatron.
"We think Q2 GDP growth will likely turn negative," said Zhiwei Zhang, president and chief economist for Pinpoint Asset Management, on Monday.
"The government faces mounting pressure to launch new stimulus to stabilize the economy," Zhang said.The leadership in China is aware of the economic pains and has taken some steps recently to bring relief.
The People's Bank of China announced Sunday that it would cut the mortgage rate for first-time homebuyers, in a move to lift the ailing property market.
Separately, the Shanghai government said the city will gradually open shops, restaurants, and salons from Monday, which will be a relief for its 25 million residents.
The government has also recently pledged to prop up the economy through more infrastructure spending and targeted monetary easing to support small businesses.
Monday's data showed investments in manufacturing increased 12.2% from a year ago. Infrastructure investment, meanwhile, rose 6.5%.
But "the risks to the outlook are tilted to the downside, as the effectiveness of policy stimulus will largely depend on the scale of future Covid outbreaks and lockdowns," said Tommy Wu, lead China economist for Oxford Economics, on Monday.

Tencent Music Entertainment Group, the leading online music and audio entertainment platform in China, today announced its unaudited financial results for the first quarter ended March 31, 2022.
We delivered a healthy 18% year-over-year growth in subscription revenues with paying users exceeding 80 million in the first quarter, as supported by our dual engine content-and-platform strategy. Despite the headwinds in an evolving market landscape, which resulted in a year-over-year decline in total revenues, our efforts to optimize cost structure and improve operating efficiency led to improved profitability quarter-over-quarter," said Mr. Cussion Pang, Executive Chairman of TME. "In an era of increasing entertainment choices, the ability to sustain a competitive advantage is awarded to those who offer users a differentiated experience. We are encouraged by the increasing benefits our original content production investments and Tencent Musician Platform have brought to our users, musicians and the overall content ecosystem. With these initiatives, we continue to make critical investments that align with our long-term strategic goals and create sustainable value for all our music stakeholders."To get more tencent news, you can visit shine news official website.

"In the first quarter, we continued to build an immersive music entertainment ecosystem, bringing music lovers innovative possibilities for how they listen, watch, sing and play. With the goal of creating a sense of belonging that makes our products a must-have, we look for ways to address the multi-faceted needs of diverse user cohorts," said Mr. Ross Liang, CEO of TME. "In the first quarter, we further strengthened our cooperation with Tencent's ecosystem in content production and promotion, with the rewards becoming increasingly manifest. In addition, our long-form audio continued to gain traction thanks to differentiated content, and we are working on improving its monetization efficiency mainly through memberships. Moving forward, we will continue to make our ecosystem, content, products and services differentiated and highly specialized. This, in turn, will help us better serve hundreds of millions of music lovers, music creators and the music industry as a whole, and unlock the massive opportunity in front of us," concluded Mr. Liang.
The year-over-year decline in online music mobile MAUs was primarily due to churn of our casual users and reduced marketing spending required by our more disciplined cost management. However, online music paying users continued to deliver robust year-over-year and quarter-over-quarter growth, reaching 80.2 million, which was attributable to our high-quality content and services, effective promotions, as well as improvement in paying user loyalty.

Social entertainment services MAUs and paying users were lower year-over-year and quarter-over-quarter, affected by industry and macro headwinds. We will continue to improve our competitiveness through ongoing product innovations and new initiatives in social entertainment such as audio live streaming, international expansion and virtual interactive product offerings.

We remained committed to strengthening our original content production capabilities, to systematically create, evaluate and promote music.
With Xingyao Plan and Galaxy Plan, we empower original content production by leveraging technology to add value across demo and singer discovery throughout the phases of production, distribution and promotion for these original works. In the first quarter, we delivered dozens of original hit songs to a broad audience, including "Mirage" and "Drown," two sweeping successes that topped multiple music charts and both achieved peak daily streams in excess of 13 million.
We achieved top rankings for our original content in key verticals such as gaming, Chinese Ancient Style and pop music. In the first quarter, we collaborated with Tencent Games' popular titles, including PUBG Mobile, Honour of Kings, League of Legends: Wild Rift to produce chart-topping original songs by leading artists such as Hua Chenyu, Chen Linong, Mao Buyi and Z.TAO.
Tencent Musician Platform cultivates budding musicians by providing them with all-round services to help showcase their talent and passion.
Established sustainable and diverse monetization models for musicians, which helps them earn a better living while focusing on honing their craft, as demonstrated by the distribution of over RMB200 million from our platform to musicians during the past 12 months.
Launched a new behind-the-scenes producer service, with more than 50 well-known industry professionals and more than 100,000 creators joining in the first quarter, as well as a customized self-service productivity toolkit to empower musicians to create and promote their works more efficiently and reach a larger audience.
Motivated aspiring talents with diverse creative scenarios and rich online and offline promotion resources, driving accelerated professional growth and broader recognition for musicians such as Liu Shuang and Georgina Qian.

Freshly squeezed juices are always refreshing and help to elevate the spirits. But, what if the peels too can be utilized somehow? Feel the Peel is a 3.1-meter tall installation, it is a motorized orange juicer that has a dome holding 1,500 oranges.To get more news about peeling juicer for orange, you can visit hl-juicer.com official website.

Italian design firm Carlo Ratti Associati has created this innovative experimental installation in collaboration with global energy company Eni.

Feel the Peel is no ordinary juicing machine. Not only it serves juice but makes sustainable cups out of orange peels at the site. When a customer orders juice, the oranges slide down from the dome into the machine. The oranges are automatically cut into half and the peels get stored in the bottom unit of the structure.

Once agglomerated, the peels are dried by the built-in machinery and turned into powder. The orange peel powder is mixed with powder Polylactic Acid bioplastic. Then the mixture is heated and melted to release into filament-form by an integrated 3D printer, creating cups to serve the juice. After the use, 3D printed bioplastic cups are deposited by customers for recycling.This prototype shows the circularity of life. It depicts the use and benefits of the approach of circularity in the environment. According to Ratti, the next iterations of Feel the Peel could print fabric for clothing from orange peels.

Feel the Peel will be demonstrating its functions to the public in several locations across Italy in the next few months. Take a look at its working mechanism in the video below.

The installation, equipped for the aseptic sterilization of the product, is composed of Deaerator Volumetric pump Sterilization section Thermal holding section Cooling section. Support structure Washing and sterilisation system Valve series - fittings Series of automatic valves Controls of the installation are provided with an electrical panel made of watertight stainless steel which is common to the aseptic filler and is installed on it.To get more news about Tubular sterilizer, you can visit hl-juicer.com official website.

Widely used for the sterilization of fruit juice, tea drinks, milk and virgin pulp and other liquid food.
UHT Sterilizer can carry out heating, heat preservation, heat recovery and cooling operations.
In the whole process of sterilization, the temperature of the material are in full automatic control.
Features

main structure is made of 304 stainless steel
Thorough sterilization, low energy consumption
All connection with steam protection
Easy to clean, with advanced structure, reliable usage.
Independent control cabinet, HMI PLC control
With aseptic filling machine carry out CIP and SIP simultaneously
Used four heating and sterilization of high viscosity products, fiber products, pulp, high acid contend products. Such as tomato paste, concentrated sauce etc.
Characteristics
Adopts four layer pipe heat exchange,raw material is treated with heat from inside out, adopts pressure release valve and temp control meter Steam adjusted valve,stainless steel electric control ark. Heating temperature can be adjusted,also equipped the reflux system when temperature is low.

Binance is a household name in the blockchain and cryptocurrency space. It is one of the world's most popular cryptocurrency exchanges. Amazing how a firm began as a simple crypto exchange but has now evolved into one of the world's most prominent crypto financial services providers.To get more news about Binance Referral ID, you can visit binance-referral-id.com official website.

Signing up for the Binance platform provides a plethora of benefits. However, using a Binance referral code can provide users with many additional benefits, such as cashback on trading fees and access to multiple rewards on the Binance referral program.

HLUT9G7Z is Binance referral code. New Binance users can use the code to receive the Binance referral bonus and unlimited discounts. In 2017, Changpeng Zhao registered Binance on Cayman Island. Binance was founded in China, but due to the Chinese government's increased control over cryptocurrencies, the firm had no choice but to move its headquarters outside of the country.

Binance is a great opportunity for anyone looking for a large market with a high level of security. It has the same features as any other exchange. By using the Binance referral code, you can earn fantastic rewards. If you sign up using the referral code, you will receive a 50% lifetime discount on trading. HLUT9G7Z is Binance referral code. You will also be eligible for a referral program kick back in addition to this discount.

If users are looking for a one-stop shop for all of their crypto needs, Binance is the platform where they can find that. As a trading and exchange platform, it enables users to buy crypto with fiat currency, exchange one coin for another, earn interest on crypto holdings, and trade crypto for profit.

Binance has a variety of ways to offer traders profit on their platform. Experts traders can trade crypto futures with increased leverage. If you want to improve your mining abilities, you can join a mining pool. Assume you live in a region where it is impossible to buy cryptocurrency directly from Binance. In that case, users use the Peer-to-Peer exchange service to trade currency locally.
Aside from that, users can become liquidity providers and earn crypto in exchange for their services or get a loan using their crypto as collateral. Finally, Binance recently launched their own NFT service, ideal for high-risk tolerance.

HLUT9G7Z is Binance referral code. You will receive maximum discount on all trading fees by applying the code and extra 20% for life. Also earn upto 50% trading commissions on each successful referral by inviting your friends to sign up with your referral code.

One of the best characteristics of Binance is that it gives consumers a lot of control over their recommendations. Let's look at joining the program, its foundations, and what is required to maximize the incentives. The referral program at Binance is primarily focused on trading discounts and commissions. Referrers who refer a new user to Binance receive a generous share of the fees whenever the new user trades on Binance as part of the requirement of the referral program.

The Binance promo code CRH6LXK8 allows new users on Binance to claim the best sign up bonus on the exchange. Just remember that users must enter this code when signing up to the platform. Accounts that have already been created will not be able to claim the welcome offer using the code.To get more news about Binance Referral ID, you can visit binance-referral-id.com official website.

The Binance referral program has both positives and negatives compared to the referral programs of other exchanges. The biggest negative is that there are other platforms out there that offer higher rewards for referring friends and family.

This is mainly due to Binance's size. Since it is already one of the largest exchanges in the world, it does not need to entice users to join the platform as much as other exchanges.

That said, the biggest advantage of the Binance referral program is that it allows users to have a lot of control over how they manage their referrals and the tactics they use.

Binance has both a referral and an affiliate program. The two are largely the same, but differ slightly in terms of scope.The Binance referral program is open to everyone, and new users can join the program as soon as they have set up their accounts. The process is simple: Users need to head to the referral program tab and generate a code.

This code can then be used by friends and family to sign up to Binance. When users refer their friends, they stand to receive up to 40% commissions on the trading fees generated by their referrals.

The commission generated by trading needs to be split between the referrals and the users who invited them. The split is determined by the user when generating a referral code.

Users need to ensure that they provide enough of a kickback to their referrals to make their invite code appear attractive. However, it is also important that they save enough of the commission for themselves that it is actually worth it for them to refer people to Binance.The Binance affiliate program is the second way for users to earn free crypto by referring people to the exchange. For the most part, it is just like the referral program. Users get a referral code that they can send out to invite people to the platform. For their trouble, they earn a commission on the trading fees.

The biggest difference between the two is that the commission rates are capped at 50% for Binance affiliates instead of 40%. This 10% higher commission rate can make a huge difference over the long run, especially considering that it applies to all the trades made by all the referrals.

The other major difference is that not anyone can become a Binance affiliate. There is an application process that users must go through. The affiliate program is for people or organizations with a large following. As such, users must be able to prove that they have a platform through which they can invite a large number of people to the platform.
Those who know even a little bit about crypto will know that Binance is one of the largest and most respected crypto exchanges out there. In fact, Binance is almost always used as a benchmark when talking about other exchanges.

Binance initially began as a simple cryptocurrency exchange. However, it has been one of the first to roll out new features as the crypto and DeFi ecosystem has progressed.

Nowadays, Binance is pretty much a complete financial institution in itself. Users of the exchange not only have access to exchanging fiat currency for crypto, but also the ability to utilize their crypto to its fullest potential.

Binance offers a lot in the way of features, so let's go through the major categories that Binance operates in and what users can do in each one.

Why Female Newscasters Have the Same Hair

Esther Katro was 22 when she landed her first job as a reporter at a local TV station in Fayetteville, Arkansas. The recent graduate loved the thrill of breaking news and being on air. But when she was out chasing stories in the college town, people kept mistaking her for a student. She went to her news director for advice, and his response had nothing to do with developing her fledgling reporting skills. “He was like, ‘You have to cut your hair to look older,’” she recalled.To get more news about wig shop, you can visit monahair.com official website.

Katro hated the idea. She’d had long, dark hair flowing well past her shoulders for her entire life. But she desperately wanted to be seen as professional. So she booked an appointment at a local salon.

“I remember sitting at my desk in Arkansas and Googling ‘short anchor hair,’ and seeing what came up,” she said. “I went [to the salon] and told them ‘I want to look older; give me a sophisticated cut to my jawline.’”

If you’ve ever tuned in to your local 6 o’clock news, or simply stared mindlessly at the CNN feed blaring on the screen by your airport gate, you’ll recognize the cut Katro got that day: hair that falls between the chin and collarbone; sleek strands are blown out to perfection, not a flyaway in sight. Light layers and a heavy coat of hairspray lift the roots and frame the face in all the right ways. It’s neither too big nor too flat, the texture magically landing somewhere between a helmet and a halo.

It's a favorite among Fox News personalities, like Martha Maccallum, Shannon Bream, and Ainsley Earhardt; you'll see it on Megyn Kelly who's now at NBC. It's not partisan — it's everywhere, from big networks to small local outfits, no matter the anchors' preferred look. “It didn’t match my age,” Katro says, “but it was a professional cut.”

It’s the omnipresent anchor bob. And it’s no coincidence. The longstanding homogeneity of on-air hair, from Topeka, Kansas to Trenton, New Jersey — reporters and industry veterans say — is by design.Hair isn’t the only way in which women are held to high aesthetic standards on TV, but it’s one of the most shapeable — and ubiquitous — elements of the newscaster uniform. So what are the so-called rules of on-air hair? Anchors, reporters, and industry experts interviewed for this piece laid them out: Wear your hair down, in a smooth style that hits at the collarbone or above. Updos and complicated styles are a no, as are drastic color changes. Youthful appearance is key (better dye those grays away!). A bit of wave is okay (and increasingly popular at some stations), but ringlets and kinky curls are not.

It's not just perception, either. Researchers at the University of Texas, Austin, analyzed more than 400 publicity images for local broadcast journalists and found that 95.8 percent of female anchors and reporters had smooth hair. About two-thirds had short or medium-length cuts. Nearly half of the women were blond. Zero had gray hair. Just one black woman in the UT study sample wore her natural curls.

The style standards are a result of longstanding requirements that female reporters not only do their jobs, but “fulfill larger audience expectations of what women are supposed to look like,” says Mary Angela Bock, a UT assistant professor and lead author of the study. That ideal look “is stereotypically heteronormative, not overly sexy, and predictable.”

Sometimes, anchors’ contracts even go as far as explicitly preventing women from changing their appearance without a manager’s approval. Stations frequently hire consultants to help increase viewership, and they make recommendations on hairstyles in addition to news segments and set design.

Kamady Rudd, now an anchor at ABC affiliate WZZM in Grand Rapids, Michigan, recalls being asked during multiple job interviews whether she’d cut her hair into something that more closely resembled an anchor bob (her current station didn’t make such a request). Consultants have told her to tease her roots to add body. “It’s one cut for everyone,” she says. “They want you to be trendy, but not too trendy. They want you to look nice, but not too nice. It has to be on this really fine line.”

Even when it’s not an explicit order, the message to women in the industry is clear. “It was always one of those things where it was like, 'We’d really like you do to this,'” she says. “I’ve never known anyone where it was an ultimatum, it was just highly suggested.”

Jana Shortal, now an anchor and reporter at the NBC affiliate KARE in Minneapolis, also felt those messages acutely throughout her early career. “One of the first things they’ll tell you as a woman in broadcast is you can’t have curly hair,” says Shortal, who, as you might guess, has naturally curly hair. “It wasn’t that I had this big, bad, mean boss-man telling me I was ugly every day. There were slight suggestions that I would hear that were like, ‘You do realize this is a visual medium?’”

REPLACE COVID Bolsters Advice to Continue RAAS Inhibitors in COVID-19 Patients

Another randomized trial, REPLACE COVID, indicates that patients already taking ACE inhibitors and ARBs when they’re hospitalized for COVID-19 should continue to do so, supporting recommendations from international CV societies.To get more news about RaaS, you can visit glprobotics.com official website.

When it came to outcomes including all-cause death, duration of mechanical ventilation, time on renal replacement or vasopressor therapy, and multiorgan dysfunction during hospitalization, there were no differences between patients who continued versus discontinued their renin-angiotensin-aldosterone-system (RAAS) inhibitors after they were admitted, researchers report in a study published online last week in the Lancet Respiratory Medicine.

Considering these findings and those from the BRACE CORONA trial, presented last year at the virtual European Society of Cardiology Congress, the message is simple, according to senior author Julio Chirinos, MD, PhD (University of Pennsylvania, Philadelphia). “In people who fall ill with COVID-19 requiring hospital admission, continuing these medications for established indications should be considered safe.”

Early after SARS-CoV-2 started circulating around the world, there were concerns that use of RAAS inhibitors might worsen the severity of COVID-19. That’s because there was some evidence that the agents increase the expression of ACE2, which has been shown to facilitate entry of the novel coronavirus into host cells.

International CV societies came out in favor of continuing ACE inhibitors and ARBs in patients hospitalized with COVID-19 while acknowledging the need for better data exploring the issue. Subsequent observational studies mostly suggested that there was no relationship between outpatient use of RAAS inhibitors and risk of COVID-19 hospitalizations or mortality, but randomized trials were launched to provide more-definitive insights.

REPLACE COVID, co-led by Chirinos and Jordana Cohen, MD (University of Pennsylvania), was a randomized, open-label trial conducted at 20 hospitals in the United States, Canada, Mexico, Sweden, Peru, Bolivia, and Argentina. It included 152 hypertensive patients (mean age 62 years; 45% women) randomized to continue or discontinue their ACE inhibitors and ARBs.

The primary outcome consisted of a global rank score that incorporated time to death; duration of mechanical ventilation or extracorporeal membrane oxygenation; time on renal replacement or inotropic or vasopressor therapy; and multiorgan dysfunction during hospitalization, assessed with the modified Sequential Organ Failure Assessment (SOFA) score. The global rank score did not significantly differ between the continuation and discontinuation arms (median 73 vs 81; P = 0.61).

There were also no differences in any of the secondary outcomes, including all-cause death (15% vs 13%; P = 0.99) and median length of the hospital stay (6 vs 5 days; P = 0.56).

Adverse events occurred in 39% of patients who continued their RAAS inhibitors and 36% of those who stopped taking them (P = 0.77). Blood pressure and serum levels of potassium and creatinine during follow-up were similar in the two trial arms.

“Our findings, derived from a prospective, multicenter, randomized, controlled design, are consistent with previously published observational studies and unpublished trial evidence, which have generally shown no difference in the risk of SARS-CoV-2 infection and COVID-19 severity among patients who are treated with ACE inhibitors or ARBs compared with those who are not,” the authors conclude.

The Best Smart Locks and Smart Lock Alternatives of 2022

Smart locks allow you to lock and unlock your door with the tap of a button on your phone, or a swipe of your fingers through connection with other devices. Connections could be wired or wireless via WiFi, Bluetooth, or the Z-wave. There are a variety of features that smart locks can offer like automatic locking, retrofitted styles, device compatibility, and much more. Your specific needs will determine what the best smart lock is for you.To get more news about smart safe lock, you can visit securamsys.com official website.

For your smart locks, you want to consider lifestyle and connectivity. Would you rather have a completely keyless lock (and risk getting locked out in case of a malfunction), or do you trust your WiFi enough to rely entirely on its connectivity to gain access to your home? There's nothing like a nicely coordinated home automation sequence. Most home security systems come with smart locks as part of the package; even if it doesn't, you want a smart lock that fits seamlessly with your existing system so you get one-touch control of everything. There are different types of locks in the market, but, you want the best door locks for home security that have some or all of these features:

Open sesame! The Wyze Lock is probably one of the best things in modern life that just makes sense. This lock opens the door for you, without you doing much (think digital doorman). The technology detects when you're near it and does the job of opening the door at the tap of a button or at the sound of your voice. No more digging through the black hole that is your purse to find your keys.

The Wyze Lock pairs easily with Alexa and other smart automation devices, giving you full control of who goes into your house. A genius feature of this device is that it doesn't lock while the door is open, so there's no risk of being locked out if you quickly take the dog out for a potty break. But if you do, you can easily open it back up by typing in your code. It's wire-free and has a functional backlight that lets you see what you're doing, even if it's pitch black at night.

If you're ready to make the switch, there's no need to break down your door or rip apart your existing deadbolt. The Wyze lock fits into your existing deadbolt and lets you "keep your key" just in case. Installation is super easy — it's only four simple steps, so virtually anyone can do it. But, for a fee, you can have an OnTech professional help with installation if you book an appointment.
What's better than seeing who's at the door through the doorbell camera? Not having to get up to let them in. The SimpliSafe lock is an easy-DIY setup that lets you grant access to your house from almost anywhere. The lock fully integrates with other security devices within the home to create a fully smart home. Its unique and beautiful design makes it accessible to only you, and (more importantly) impenetrable by others.

There's no leaving out ADT's Kwikset smart lock from this list — it's just ?too? fantastic. This lock lets you arm and disarm your security system like other locks, but it goes a step further. Because it comes as part of a smart home automation package, it allows you to remotely arm your system and turn on interior lights if you see someone strange approaching your house through a video doorbell or security camera. This feature lets you fend off potential troublemakers from your home even when you're not around. Everything with this lock is programmable, from the arm and disarm times, the automatic locks, custom codes for family members, and the lock's finished surface that will match your door's aesthetics. It's also battery operated which makes it near impossible to be locked out of your home in case of a power failure of any kind.

In the array of smart locks produced by Honeywell, this particular lock stands out. Its unique design and upgraded features make it better than most. It offers one-time codes — as well as code storage for up to 50 codes — and when they include a "vacation mode" feature, you know that no one is going in (not without your knowledge at least). The lock works well when connected with the Honeywell Gateway for seamless smart home automation. It works via Bluetooth and pairs with your phone to give you full control over who goes in and out from the palm of your hand. It'll also alert you if there's a forced entry (or an attempt at one) i.e., too many failed attempts to open the lock with wrong codes.

This is a traditional wood-style door that looks classic on the outside but packs a punch on the inside. It's a screen door, so it gives you everything you love about screen doors — the views and the breeze — but with safety. In other words, they can see inside, but can't get in. Prime-Line is well-known for making easy-to-install doors and windows. This door is no different; when you purchase this security door, it comes with all the parts you need to install it yourself, along with step-by-step paper and video instructions. But, if you can't be bothered with installing a heavy door by yourself, you can have a professional come to do it for you.

The four types of COVID-19 vaccine

Over the past month, a number of COVID-19 vaccines have been approved for general or emergency use in the Middle East and North Africa (MENA). Understandably, there remains confusion over which one to choose – for example, should it be based on technology? On which one has the most advantages? Or simply on the one a country’s government chooses?To get more news about sinopharm update, you can visit shine news official website.

We’re not here to tell you which type of vaccine to choose - that is, and should be, your own choice. However, what we can agree on is that all vaccines work by exposing the human body to particles or molecules that trigger an immune response, thus protecting the subject from future infection. The key difference between the four main types of vaccines is the method of exposure used.
What to know: The whole virus vaccine uses a weakened or deactivated form of the pathogen that causes COVID-19 to trigger protective immunity to it.

The two vaccines mentioned above – Sinopharm and Sinovac – both use inactivated pathogens, therefore they cannot infect cells and replicate, but can trigger an immune response.

Benefits: According to Gavi, the Vaccine Alliance (GAVI), the advantages of an inactivated whole virus vaccine include the fact its technology is well established, it is suitable for people with compromised immune systems, and it’s relatively simple to manufacture.What to know: Since no other existing licensed or approved vaccine uses this type of technology, the Messenger RNA (mRNA) variety could be mistaken for something completely new to healthcare. However, a number of mRNA vaccines have been studied in the past for illnesses and diseases including cytomegalovirus (CMV), influenza, rabies, and the Zika virus.

According to the Centers for Disease Control and Prevention (CDC): “Researchers have been studying and working with mRNA vaccines for decades. Interest has grown in these vaccines because they can be developed in a laboratory using readily available materials. This means the process can be standardised and scaled up, making vaccine development faster than traditional methods of making vaccines.”

So how does it reportedly work? The COVID-19 RNA vaccine consists of mRNA molecules made in a lab that code for parts of the SARS-CoV-2 virus – specifically the virus’ spike protein.

Once injected into the body, the mRNA instructs the cells to produce antigens – such as the spike protein mentioned – which are then detected by immune cells, triggering a response by the body’s lymphocytes.

The killer T-cells destroy the infected cells, while the B-cells and helper T-cells support antibody production. Whoever is exposed to the COVID-19 coronavirus in the future would have an immune system that recognises it, and in turn fight off the infection.

Benefits: According to the University of Cambridge’s PHG Foundation, advantages include good safety (since there are no live components, there’s no risk of the vaccine triggering disease), reliability, and that it’s relatively simple to manufacture.

Challenges: Disadvantages include unintended effects (such as an unintended immune reaction), ensuring effective delivery into the body (since free RNA in the body is quickly broken down), storage issues, plus the fact that this type of vaccine has never previously been licensed for humans.What to know: This type of vaccine introduces a safe, modified version of the virus – known as “the vector” – to deliver genetic code for the antigen. In a COVID-19 vaccine, the “vector” is the spike proteins found on the surface of the coronavirus.

Once the body’s cells are “infected”, the cells are instructed to produce a large amount of antigens, which in turn trigger an immune response.

Benefits: Viral vector-based vaccination is another well-established technology that can trigger a strong immune response as it also involves both B cells and T cells.

Challenges: Previous exposure to the vector could reduce effectiveness, plus these types of vaccines are relatively complex to manufacture compared to others.